Cal v. San Diego State Football 2025 Betting Odds and Lines
The California Golden Bears are big favorites against the San Diego State Aztecs, according to the latest odds
The California Golden Bears (3-0) are favorites to beat the San Diego State Aztecs (1-1) on Saturday, according to sportsbooks’ college football lines and odds.
Cal v. San Diego State college football betting pick, odds and lines: Who is favored to win?
The latest college football betting odds for Cal v. San Diego State are between Cal -12 and Cal -12.5, as of Wednesday morning, according to data independently collected and viewed by Write for California.
The Cal -12.5 line implies the California Golden Bears are 12.5-point favorites over the San Diego State Aztecs.
The latest point totals for Cal v. San Diego State for “over-or-under” total score bets, as of Wednesday morning, are between 48 and 48.5 points, according to data independently collected and viewed by Write for California.
The Cal -12.5 line and 48.5-point total imply Cal will beat San Diego State with a scoreline of approximately 31-18.
Cal v. San Diego State “moneyline” bets range between Cal -450 and Cal -520 and San Diego State +340 and San Diego State +385, as of Wednesday morning, according to data independently collected and viewed by Write for California.
Moneyline bets pay out based on the Cal v. San Diego State game’s result, regardless of the “point spread” handicap or the margin of victory.
Someone would need to bet $450 on Cal’s most favorable moneyline of Cal -450 to profit $100, while a San Diego State moneyline wager pays a $385 profit on a $100 bet if the Aztecs win outright at San Diego State’s most favorable +385 moneyline.
Cal v. San Diego State college football: What you should know
This Saturday’s match-up between Cal and San Diego State will be the 10th game in the series. Cal has a 5-4 lead in the series, but has lost every single game played in San Diego. The Golden Bears last beat the Aztecs on Sept. 14, 2024, a 31-10 win at home.
San Diego State will face undefeated Cal at home after sitting idle last week.
The California Golden Bears are 2-0 against the spread this season, while the San Diego State Aztecs are 0-1 with a point handicap.
According to Vegas Insider, which collects and reports sportsbooks’ college football odds and lines, 61% of all Cal v. San Diego State total score bets, as of Wednesday morning, have been on an “over” result. Cal has had one “over” game and one “under” game this season, while San Diego State has had one game over the total.
Vegas Insider reports that the Cal v. San Diego State line opened earlier this week at around Cal -11.5. In other words, over the week, the spread moved one point toward Cal, when compared to the Cal -12.5 line, meaning bettors generally believe Cal will win by a double-digit margin. However, Circa Sports’ line opened at Cal -13.5 on Sunday.
The Cal v. San Diego State college football moneyline opened early this week at about California -500 and San Diego State +380, according to Vegas Insider.
Vegas Insider reports that the Cal v. San Diego State total opened at about 48.5 points earlier this week. Circa Sports opened with a 53-point total on Sunday.



Cal should win, but this has all the signs of a “trap game”! We’d better not get too full of ourselves heading into an away game in an unfriendly environment against a team with nothing to lose! I’ve seen us lay an egg in San Diego before, but hoping we have the coaching and team leaders to overcome this and have a BIG win! Go Bears!
Taking Cal to beat the spread all day