Cal v. Virginia College Football 2025 Betting Odds and Lines

The California Golden Bears are underdogs in their match-up against the Virginia Cavaliers, according to the latest odds

The California Golden Bears (5-3, 2-2 ACC) are underdogs in their match-up against the Virginia Cavaliers (7-1, 4-0 ACC), according to the latest college football lines and odds offered by sportsbooks.

Cal v. Virginia college football betting pick, odds and lines: Who is favored to win?

According to data independently collected by Write for California, the latest college football betting odds for Cal v. Virginia is a consensus Cal +4.5, as of Thursday morning.

The Cal +4.5 line implies the California Golden Bears are about five-point underdogs to the Virginia Cavaliers.

According to data independently collected by Write for California, the latest point totals for Cal v. Virginia college football “over-or-under” total score bets are between 52.5 and 53.5 points, as of Thursday morning.

The Cal +4.5 line and 52.5-point total imply the California Golden Bears will lose to the Virginia Cavaliers with a scoreline of about 24-28.

According to data independently collected by Write for California, the latest Cal v. Virginia college football “moneyline” ranges between Cal +143 and Cal +170 and Virginia -182 and Virginia -205, as of Thursday morning.

Moneyline bets pay out based on the Cal v. Virginia college football game’s result, regardless of any point “spread” handicap or margin of victory.

A bet on Cal’s most favorable moneyline of Cal +170 pays a $170 profit with a $100 wager, and a wager on Virginia’s most favorable moneyline of Virginia -182 requires a $182 bet to win $100.

Cal v. Virginia college football: What you should know

The California Golden Bears and Virginia Cavaliers meet for the first time on Saturday, Nov. 1, 2025.

Cal has never played a nationally ranked top-25 team this season. The Virginia Cavaliers are ranked No. 15 in the country and one of 23 teams with one or no losses.

The California Golden Bears are 3-1 when playing at home, while the Virginia Cavaliers have a 2-1 on the road this season.

Last week, the California Golden Bears lost in the second overtime period, 34-42, at Virginia Tech. Virginia is coming off a 17-16 overtime win against the North Carolina Tar Heels in Chapel Hill, N.C.

According to Vegas Insider, which analyzes and aggregates sportsbooks’ offered odds and lines, the Cal v. Virginia college football line opened earlier this week at about Cal +4. The Cal v. Virginia line opened at Cal +3 this week at Circa Sports.

Vegas Insider reports the Cal v. Virginia moneyline opened earlier this week at about Cal +145 and Virginia -175, and the total opened at about 54.5 points.

The California Golden Bears are 3-4 against the spread so far in the 2025 college football season, while the Virginia Cavaliers are 4-3 against the spread.

According to Vegas Insider’s analysis, 54% of bets on the Cal v. Virginia college football game with a point spread have been on the California Golden Bears, 54% of over-or-under total score bets have been on the over and 85% of moneyline bets have been on the favorites, the Virginia Cavaliers.