Cal v. Virginia Tech College Football 2025 Betting Odds and Lines

The California Golden Bears are slight underdogs in their upcoming match-up against the Virginia Tech Hokies, according to the latest odds

Lane Hall on the campus of Virginia Tech in Blacksburg, Va.

The California Golden Bears (5-2, 2-1 ACC) are underdogs in their upcoming match-up against the Virginia Tech Hokies (2-5, 1-2 ACC), according to the latest college football lines and odds offered by sportsbooks.

Cal v. Virginia Tech college football betting pick, odds and lines: Who is favored to win?

According to data independently collected by Write for California, the latest college football betting odds for Cal v. Virginia Tech are between Cal +4.5 and Cal +5.5, as of Thursday morning.

The Cal +4.5 line implies the California Golden Bears are about five-point underdogs to the Virginia Tech Hokies.

According to data independently collected by Write for California, the latest point totals for Cal v. Virginia Tech college football “over-or-under” total score bets are a consensus 50.5 points, as of Thursday morning.

The Cal +4.5 line and 50.5-point total imply the California Golden Bears will lose to the Virginia Tech Hokies with a scoreline of about 23-27.

According to data independently collected by Write for California, the latest Cal v. Virginia Tech college football “moneyline” range between California +165 and Cal +180 and Virginia Tech -195 and Virginia Tech -220, as of Thursday morning.

Moneyline bets pay out based on the Cal v. Virginia Tech college football game’s result, regardless of any point “spread” handicap or margin of victory.

A bet on Cal’s most favorable moneyline of Cal +180 pays a $180 profit on a $100 wager. In contrast, a moneyline bet on Virginia Tech’s most favorable moneyline of Virginia Tech -195 requires a $195 bet to earn a $100 profit.

Cal v. Virginia Tech college football: What you should know

The California Golden Bears are 1-0 against the Virginia Tech Hokies. The two teams last played each other in the 2003 Insight Bowl in Phoenix, having never met in the “regular” season. The Golden Bears, then led by quarterback Aaron Rodgers, won 52-49 in an offense-packed, down-to-the-wire contest.

Virginia Tech hosts Cal after a bye last week. This is the fourth time this season that the California Golden Bears are playing a team off a bye. San Diego State blanked Cal after sitting idle the previous week, while the Golden Bears defeated the Boston College Eagles and North Carolina Tar Heels when they came off their bye.

Virginia Tech’s last game was a 20-35 loss at Georgia Tech on Oct. 11, 2025. Last week, the California Golden Bears hosted North Carolina, beating the Tar Heels, 21-18.

According to Vegas Insider, which analyzes and aggregates sportsbooks’ offered odds and lines, the Cal v. Virginia Tech college football line opened earlier this week at about Cal +2.5. Over the week, the line moved about two points in Virginia Tech’s favor, meaning the Hokies have become bigger favorites to win.

Vegas Insider reports the Cal v. Virginia Tech moneyline opened early this week at about Cal +164 and Virginia Tech -198. The site also reports the Cal v. Virginia Tech opened at about 50.5 points, unchanged from the latest offered total, as of Thursday morning.

The California Golden Bears are 3-3 against the spread in the 2025 college football season, while the Virginia Tech Hokies are 1-5.

According to Vegas Insider’s analysis, 52% of bets with a point spread have been on Virginia Tech, while 76% of moneyline bets have been wagered on the Hokies to beat the Golden Bears outright. Vegas Insider also reports that only a small majority (51%) of Cal v. Virginia Tech total score wagers have been on the “under.”